A Bold Treatment.
A Hopeful Future.
When other cancer treatments stopped working, we didn’t. Backed by 16 years of research and ongoing FDA clinical trials, our proprietary treatment is a less invasive, more precise way to treat multiple types of cancer.
The only Dendritic Cell Treatment that creates vetted significant Killer T Cell activity.
Step 1: Cell Processing
Immunocine’s unique protocol starts in our laboratory after we have collected a patient’s white blood cells and a sample of the tumor.
Using a variety of techniques, a patient’s Biopsied Cancer Cells are broken down into mRNA and Cancer Antigens specific to the cancer.
The cancer specific mRNA and proteins are then isolated and prepared for loading into a patient’s Dendritic Cells. As a note, there are no intact cancer cells after the cell processing!
Step 2: Dendritic Cell Loading
While still in the laboratory, the cancer specific mRNA and Antigens are presented to the patients Dendritic Cells internally and externally.
The cancer mRNA is loaded inside the Dendritic Cell, which provides important cancer “blueprint” information to the immune cell in much the same way as a virus would be primarily detected.
Total cancer antigens are loaded on the outside of the Dendritic Cell, allowing it to detect important target and mutational information needed to properly train the rest of the immune system.
Step 3: Dendritic Cell Activation
Once a Dendritic Cell detects matching cancer mRNA and mutated antigens, it knows that there is a cellular threat in need of elimination. This is similar to the removal of virally-infected cells, and a targeted immune response is underway.
The Dendritic Cell compares antigens simultaneously found on both “inside” and “outside” pathways, reacting powerfully and uniquely when a match is found. This phenomenon cannot be replicated by other methods.
The Dendritic Cell releases unique signals to nearby immune cells (e.g., NK cells, Killer T cells) that the body deploys to find, fight, and destroy an “infection” such as this. Since Immunocine uses the patient’s own cancer antigens to create this response, the immune system ramps up to specifically attack these same cancer cells throughout the body!
Complete
Our Dendritic Cell Treatment initiates a complete Immune Response against your cancer cells.
This top-down approach avoids the unspecific and ineffective targeting of other Immunotherapies.
Natural
Our Dendritic Cell Treatment does not introduce any foreign compounds or genetically modified cells into the body.
By using your body’s own cells, our treatment significantly reduces the risk of side effects.
Ongoing
Our Dendritic Cell Treatment fully activates the Immune System and therefore continues after patients have received their last treatment.
This Immunological Memory can make it much harder for the cancer to return.
A First in Dendritic Cell Treatments
Found throughout the body’s tissues, Dendritic Cells lie in wait for threats such as viruses, bacteria, parasites, and mutated cells. Once a Dendritic Cell is properly aware of a threat, it will digest and learn the nuances of this threat, and quickly migrate to the nearest lymph node to initiate an optimal attack against the threat. They are the “Generals” of the immune system.
INTERFERON GAMMA CONCENTRATION
“TUMOR-KILLING POTENTIAL”
Decker, W.K.et al. Th-1 polarization is regulated by dendritic-cell comparison of MHC class I and class II antigens. Blood 113, 4213-4223 (2009).
Once a Dendritic Cell activates the Killer T cells, the T cells release a compound called Interferon Gamma. The higher concentration of Interferon Gamma leads to a stronger immune attack, which generates a red spot in the laboratory.
A Complete Immune Response
Dendritic Cells have the natural ability to initiate an immune response. This natural ability eliminates the need for artificial medications or genetically modified cells.
Key to Natural Anti-Tumor Immunity
Dendritic Cells activate Natural Killer and Killer CD8 T cells, which are widely recognized as the major antitumor mechanism of the immune system. This natural ability allows Dendritic Cell Treatments to take advantage of existing immune system processes.
Target Multiple Cancer Mutations
Dendritic Cell Treatments can simultaneously attack multiple cancer markers and avoid the singular targeting issues of other immunotherapies.
The Immunocine Dendritic Cell Treatment (IDCT) Estimated Timeline
Spread over the course of six weeks, our treatment protocol is a unique and comprehensive immunotherapy focused solely on activating a natural and aggressive immune response against our patient’s cancer. While every patient receives a personalized treatment, our protocol is the same for every patient.
After arriving in Cancún, a private driver will take you from the airport to wherever you are staying. Once settled, one of the Immunocine physicians will meet you at your lodging to introduce themselves and welcome you to Cancun. We will also take a few blood samples to establish your medical baseline prior to treatment.
To boost your white blood cell count and prepare your Immune System for the Immunocine Dendritic Cell Treatment (IDCT), a member of the medical team will visit you for a subcutaneous injection of Neupogen (G-SCF), which is a natural cytokine found in your body.
To educate your Immune System, our team will need a sample of your tumor. Our Radiologist, Dr. Viramontes, will perform your biopsy at a full-service, private hospital.
To extract the Dendritic Cells that will be fighting your cancer, you will go through a process called Apheresis. The white blood cells obtained during Apheresis will ultimately be turned into Dendritic Cells.
Our team of Molecular Biologists will now start making your personalized treament in our state-of-the-art laboratory.
In this process, our team will break down your cancer cells to unique and complete genetic markers. With these total cancer markers, we will train your Dendritic Cells to recognize the cancer cells expressing these markers as dangerous cells that must be destroyed immediately.
Now that your treatment has been created, you are ready to receive your first Dendritic Cell Treatment. Dr. Viramontes will administer the first treatment via an Ultrasound-Guided Injection at a full-service, private hospital. This process takes no longer than 15 minutes and is completely outpatient. You will now wait two weeks until you receive your second injection. Many patients choose to return home during this waiting period.
After two weeks, your Immune System will be ready for the second boost. This follows the same process as on Day 15, and is supported by pre- and post- analysis and consultations to ensure safety and appropriate activity
After two weeks, your Immune System will be ready for the final boost. Following the exact same process as before, Dr. Viramontes will perform the third injection at a full-service, private hospital.
After arriving in Cancún, a private driver will take you from the airport to wherever you are staying. Once settled, one of the Immunocine physicians will meet you at your lodging to introduce themselves and welcome you to Cancun. We will also take a few blood samples to establish your medical baseline prior to treatment.
To boost your white blood cell count and prepare your Immune System for the Immunocine Dendritic Cell Treatment (IDCT), a member of the medical team will visit you for a subcutaneous injection of Neupogen (G-SCF), which is a natural cytokine found in your body.
To educate your Immune System, our team will need a sample of your tumor. One of our Interventional Radiologists, will perform your biopsy in a safe, regulated manner.
To extract the Dendritic Cells that will be fighting your cancer, you will go through a process called Apheresis. The white blood cells obtained during Apheresis will ultimately be turned into Dendritic Cells.
Our team of Molecular Biologists will now start making your personalized treament in our state-of-the-art laboratory.
In this process, our team will break down your cancer cells to unique and complete genetic markers. With these total cancer markers, we will train your Dendritic Cells to recognize the cancer cells expressing these markers as dangerous cells that must be destroyed immediately.
Now that your treatment has been created, you are ready to receive your first Dendritic Cell Treatment. This will be an ultrasound guided injection near functional, cancer-proximal lymph nodes performed by an Immunocine-trained interventional radiologist. This process is relatively brief and is completely outpatient unless medically deemed otherwise. Your immune system will now begin to ramp up over the next 2 weeks before your second Dendritic Cell boost maximizes the immune capabilities. This injection may be followed by increasing the Type I interferons circulating throughout your body, an important component to the entire body readying for a proper Th1-immune fight. Many patients choose to return home during this waiting period.
After two weeks, your Immune System will be ready for the second boost. This follows the same process as on Day 15, and is supported by pre- and post- analysis and consultations to ensure safety and appropriate activity.
After two weeks, your Immune System will be ready for the final boost. Following the exact same process as before, Dr. Viramontes will perform the third injection at a full-service, private hospital.
After arriving in Cancún, a private driver will take you from the airport to wherever you are staying. Once settled, one of the Immunocine physicians will meet you at your lodging to introduce themselves and welcome you to Cancun. We will also take a few blood samples to establish your medical baseline prior to treatment.
To boost your white blood cell count and prepare your Immune System for the Immunocine Dendritic Cell Treatment (IDCT), a member of the medical team will visit you for a subcutaneous injection of Neupogen (G-SCF), which is a natural cytokine found in your body.
To educate your Immune System, our team will need a sample of your tumor. One of our Interventional Radiologists, will perform your biopsy in a safe, regulated manner.
To extract the Dendritic Cells that will be fighting your cancer, you will go through a process called Apheresis. The white blood cells obtained during Apheresis will ultimately be turned into Dendritic Cells.
Our team of Molecular Biologists will now start making your personalized treament in our state-of-the-art laboratory.
In this process, our team will break down your cancer cells to unique and complete genetic markers. With these total cancer markers, we will train your Dendritic Cells to recognize the cancer cells expressing these markers as dangerous cells that must be destroyed immediately.
Now that your treatment has been created, you are ready to receive your first Dendritic Cell Treatment. This will be an ultrasound guided injection near functional, cancer-proximal lymph nodes performed by an Immunocine-trained interventional radiologist. This process is relatively brief and is completely outpatient unless medically deemed otherwise. Your immune system will now begin to ramp up over the next 2 weeks before your second Dendritic Cell boost maximizes the immune capabilities. This injection may be followed by increasing the Type I interferons circulating throughout your body, an important component to the entire body readying for a proper Th1-immune fight. Many patients choose to return home during this waiting period.
After two weeks, your Immune System will be ready for the second boost. This follows the same process as on Day 15, and is supported by pre- and post- analysis and consultations to ensure safety and appropriate activity.
After two weeks, your Immune System will be ready for the final boost. Following the exact same process as before, Dr. Viramontes will perform the third injection at a full-service, private hospital.
A NEW DAY
Treatment Complete
The third and final Dendritic Cell Treatment marks the end of the IDCT. You will now have an active and ongoing, specific fight against the cancer in your body, meaning the treatment will continue long after you have gone home.
Shortly after completing your treatment, you will receive a Treatment Summary document outlining all testing and evaluations. Our team will continue to stay in touch with you and your physicians to monitor your progress and provide feedback until there is no more cancer to fight.
